HomeMedical Specialty FeaturesPaediatricsUniversity Children’s Hospital Zurich: World-class paediatric epilepsy surgery in Zurich

University Children’s Hospital Zurich: World-class paediatric epilepsy surgery in Zurich

When a child has severe epilepsy, families need more than treatment: they need a clear diagnosis, an expert second opinion, and a team offering the full spectrum of modern care. The University Children’s Hospital Zurich is Switzerland’s largest children’s hospital and one of Europe’s leading centres for specialised paediatric care. In our new hospital, children and families are cared for in a calm, family ­centred environment designed around safety, comfort, and recovery.

Our paediatric epilepsy programme is the largest in Switzerland and among the larg­est in Europe. Care is provided by interna­tionally recognised paediatric epilepsy ex­perts who lead international ILAE surveys, develop consensus statements and clinical guidelines, and conduct benchmark studies in paediatric epilepsy surgery. This interna­tional leadership is brought directly to each child’s diagnostic evaluation, treatment planning, and long-term care.

We provide comprehensive care for in­fants, children, and adolescents with dif­ficult-to-treat epilepsy, developmental and epileptic encephalopathies, and complex structural brain disorders. Families from the Middle East have access to a special­ised multidisciplinary team, including pae­diatric epileptologists, neuropsychologists, neuroradiologists, neurosurgeons, inten­sive care specialists, rehabilitation experts, specialised nurses, and international pa­tient coordinators.


Early evaluation and advanced diagnostics
Epilepsy surgery is no longer considered a last resort. For carefully selected children with focal structural epilepsy, surgery can offer sustained seizure freedom, reduce an­tiseizure medication burden, and improve development, behaviour, learning, and quality of life. Early referral is important: if seizures continue despite two appropri­ate antiseizure medications, or if a child has a clearly defined lesion in a surgically accessible brain area, expert presurgical evaluation should be considered without delay. Young children, including infants, can also benefit from early assessment in experienced paediatric centres.

In Zurich, we provide the full spectrum of modern paediatric presurgical evalua­tion: high-resolution epilepsy MRI, long­-term video-EEG monitoring, advanced EEG analysis, PET, functional imaging, neuropsychological and developmental assessment, genetic evaluation, and mul­tidisciplinary case review. When non­invasive tests are not sufficient, we offer invasive monitoring with stereoelectroen­cephalography (SEEG), using an individu­ally tailored strategy to define the seizure onset zone while preserving critical func­tions such as language, motor function, and vision.

Personalised surgical treatment
Our surgical expertise covers the full range of modern paediatric epilepsy surgery. De­pending on the child’s diagnosis, this may include focal resections, lesionectomies, temporal and extratemporal surgery, mul­tilobar surgery, hemispherotomy, corpus callosotomy, disconnection procedures, and minimally invasive approaches such as SEEG-guided radiofrequency thermocoag­ulation and laser ablation in selected cases. We treat focal cortical dysplasia, low-grade epilepsy-associated tumours, hypotha­lamic hamartoma, hemimegalencephaly, polymicrogyria, Sturge-Weber syndrome, tuberous sclerosis complex, Rasmussen encephalitis, vascular lesions, and MRI-negative epilepsy.

Every recommendation is personalised and discussed with parents in clear lan­guage. Referral for presurgical evaluation does not mean that surgery is inevitable; it means that the child’s epilepsy is analysed in depth so that the safest treatment pathway can be identified. When surgery is appropri­ate, the goal is not only seizure control, but also to support cognitive development, in­dependence, schooling, and family life.

Personal support for international families
International families are supported from first contact through to follow-up care. The International Office helps with medi­cal document review, appointments, cost estimates, visa and travel questions, ac­commodation, Arabic translation services, and coordination with referring physicians at home, including structured reports to ensure continuity of care.

For families seeking a second opinion or advanced treatment, Zurich offers inter­nationally recognised expertise, advanced diagnostics, surgical technology, and com­passionate paediatric care in one special­ised centre, with the child and family at the centre of every decision.

How to find the University Children’s Hospital Zurich
Send medical documents in English and, if available, imaging files to international@kispi.uzh.ch or call
+41 44 249 28 28.

  • You will receive a specialist assessment and a transparent overview of costs.
  • The International Office provides support with visas, travel, and accommodation.
  • An experienced team will welcome you on site, plan your treatment individually, and support you throughout your stay.
University Children's Hospital Zurich

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