Siemens Healthineers has launched Syngo.CT Coronary Cockpit, a new artificial intelligence-driven software solution designed to enhance the management of coronary artery disease through automated plaque analysis and percutaneous coronary intervention planning.
Software addresses growing clinical demands
The new software operates within the Syngo.via platform and supports both dual-source and photon-counting computed tomography scanners. With coronary artery disease remaining the leading cause of death globally and a major contributor to disability, the software aims to provide clinicians with efficient, minimally invasive diagnostic and treatment planning capabilities. The solution uses AI-based segmentation, labelling, and visualisation to characterise both the quantity and morphology of coronary plaque, extracting critical information embedded within cardiac CT images.
Dr Balint Szilveszter from the Heart and Vascular Centre at Semmelweis University in Budapest explained the clinical utility: “There is a lot of information that is locked within CT images. Syngo.CT Coronary Cockpit is an automated tool that provides a fast approach to unlock this information to include it in our everyday clinical routine. The information can be used for optimising medical therapy or to plan PCI procedures before even entering the cath lab.”
Reducing unnecessary invasive procedures
Traditional approaches to suspected or confirmed coronary artery disease frequently involve referral to the catheterisation laboratory for diagnostic procedures, many of which could potentially be avoided. The development of cardiac CT, particularly with dual-source and photon-counting scanners, has established non-invasive coronary CT angiography as a frontline diagnostic tool. Studies involving the Naeotom Alpha CT scanner from Siemens Healthineers, which combines photon-counting technology with dual-source capabilities, have demonstrated the ability to reduce referrals for diagnostic angiography by more than half whilst lowering costs and shortening hospital stays.
Integration with interventional planning
The software provides detailed information on plaque composition, size, and distribution, supporting clinicians in risk assessment and treatment selection. Integration with Siemens Healthineers’ dual-source and photon-counting CT scanners enables high native temporal resolution, contributing to clinical accuracy and operational efficiency throughout the coronary artery disease care pathway.
Enhanced catheterisation laboratory efficiency
By making detailed anatomical and morphological information available prior to interventional procedures, the software may enhance catheterisation laboratory efficiency and optimise resource utilisation. Clinicians gain access to comprehensive overviews of coronary anatomy and pathology, supporting more precise plaque assessment and informing key intraprocedural decisions including lesion preparation, stent length selection, and landing-zone determination.
Philipp Fischer, head of Computed Tomography at Siemens Healthineers, stated: “With Syngo.CT Coronary Cockpit, we combine our expertise in CT imaging and interventional therapy to help people with coronary artery disease live longer, healthier lives. This joint approach paves the way for a future where CT not only diagnoses but actively guides treatment decisions. It marks an important step toward CT-guided PCI and brings us closer to personalised, minimally invasive care.”
The software is pending 510(k) clearance and is not yet commercially available in the United States. In fiscal 2025, which ended on 30 September 2025, Siemens Healthineers employed approximately 74,000 people worldwide and generated revenue of around €23.4 billion.
- For more information, visit: https://www.siemens-healthineers.com/angio/lp/artis-portfolio
